A pharmacist has prepared powders including extract of belladonna in the amount of 0,015 per dose. For ten doses he had to take the following amount of dry extract:
- 0,3 g
- 0,15 g
- 1,5 g
- 0,03 g
- 0,015 g
A pharmacy prepared a solution of macromolecular substance with limited swelling capacity. What solution was labelled "warm up before use"?
- Methyl cellulose
A dispensing chemist can recommend a drug made from seeds of Aesculus hippocastanum to be taken as a veintonic and antithrombotic agent to treat venous congestion and veins dilatation of lower extremities. This drug is:
Specify the normal spoilage ratio for toxic drugs, which should be taken into account by an inventory committee during stock-taking.
- No norm defined
A schedule of sanitation actions in pharmacies is regulated by the relevant normative documents. Cleaning day at a pharmacy must be scheduled for at least 1 time:
- In a month
- In a week
- In 3 days
- In 10 days
- In 5 days
Specify which of the alkaloids given below will react positively to xanthines (murexide test):
- Atropine sulfate
- Papaverine hydrochloride
- Quinine sulfate
- Ephedrine hydrochloride
Point out the type of labour division structure of management personnel:
Losartan is contraindicated for treatment of arterial hypertension in case of:
- Urine acid diathesis
Which of the drugs listed below is used for thrombolytic therapy of myocardial infarction?
- Acetylsalicylic acid
An organisation has been founded to carry out several interconnected purposes. What type of organisation is it?
Representatives of pharmaceutical companies have met to discuss urgent issues of their further work. This meeting belongs to the following type of organizational groups (teams):
- Informal groups
- Managed groups
- Formal groups
- Role groups
Bellasthesin is a spasmolytic drug used in treatment of gastrointestinal diseases. What substance contained in Atropa Belladonna provides such an effect of the drug?
Stinging nettle (Urtica dioi-ca) leaves are mostly used as a hemostatic in tinctures and liquid extract to treat lung, intestinal, and uterine hemorrhages. What bioactive substance provides hemostatic effect?
- Vitamin K
Vitali-Morin’s reaction is used to identify tropane alkaloids in raw herbal material. Name the alkaloid that can be detected by this specific reaction.
Coumarins are natural compounds with their structure based on an benzo-alpha-pyrone skeleton. What reaction allows to detect this group of compounds?
- Lactone test
- Cyanide test
- Iron (III) chloride reaction
- Wilson’s reaction
- Trim-Hill reagent
The following raw herbal material was delivered for analysis: capi-tulum inflorescence is semicircular or conic in shape; no pedicles or only their remains; floral disk is naked, conic, hollow. Semiflorets are white, disk florets are yellow, involucres are yellow-green. The smell is specific, aromatic. The taste is bitter-spicy. What raw herbal material is it?
- Flores Chamomillae
- Flores Arnicae
- Flores Calendulae
- Flores Helichrysi arenarii
- Flores Millefolii
Standard raw herbal material of lily-of-the-valley is obtained by drying it at a temperature of 50-60°C in order to prevent the possibility of the following biochemical process:
- Enzymatic hydrolysis of cardiac glycosides
- Oxidation of phenolic compounds
- Volatilization of essential oils
- Oxidation of resins
- Oxidation of terpenoids
A patient with heart failure induced by long-term coronary vessel disorder can be administered a drug produced out of the following raw herbal material:
- Hawthorn berries
- Calendula flowers
- Ginseng roots
- Aralia roots
- Berberis roots
A patient came to a pharmacy and ordered cowberry leaves. Which of the available raw herbal materials can be offered as a substitute?
- Folium Uvae ursi
- Rizoma Calami
- Rizoma et radix Sanquisorbae officinalis
- Herba Achilleae millefolii
- Radix Taraxaci officinalis
Specify the pricing strategy of international market, which foresees establishing relatively low prices to work up the developed countries market.
- Penetration strategy
- Premium pricing strategy
- Differential pricing strategy
- Price skimming strategy
- Price leveling strategy
Point out the type of group poll that foresees a single survey of several experts to discuss a certain problem.
- Focus group
Name the stage of drug life cycle that is characterized by maximal sales and profit, and reminder advertising.
- Maturity and saturation
- Market exit
The following fruit was received for analysis: succulent drupes circular or elongated-ellipsoid in shape, 4-12 mm in length. The colour of fruit varies from yellow to dark orange. The smell is faint. The taste is sour-sweet. What plant is it?
- Hippophae rhamnoides
- Ammi majus
- Aronia melanocarpa
- Vaccinium myrtillus
- Coriandrum sativum
Cumulating drugs - Digitoxin and Cordigitum - are used to treat chronic cardiac insufficiency. What plant is used as a raw material to produce them?
- Digitalis purpurea
- Strophanthus kombe
- Adonis vernalis
- Convallaria majalis
- Erysimum canescens
Business trip can be assigned to employees only with their consent, if these employees are:
- Women with children from 3 to 14 years of age
- Women with children from 1 to 3 years of age
- Women with children less than 1 year old
- Any employee
- Women with two children
An analytical chemist working at a pharmacy identifies oxacillin sodium salt. As a reagent he uses hydroxylamine hydrochloride solution in presence of sodium hydroxide solution and copper nitrate solution. What structural fragment of the drug molecule can be detected by these reagents?
- Beta-lactam cycle
- Thiazolidine cycle
- Isoxazole cycle
- Furan cycle
- Thiadiazole cycle
A pharmaceutical enterprise that has achieved high sales rates and customers’ recognition will reach the highest profit at the following stage of the product life cycle:
- Market penetration
A factrory workshop producing suspensions and emulsions is developing manufacture of new drugs. What mechanisms can be used for ultrasound production of drugs?
- Liquid whistle, magnetostrictive source
- Dismembrator, electrical impulse plasmolyzer
- Disintegrator, liquid whistle
- Rotor-pulsation apparatus, di-smembrator
- Centrifugal mixer with rotating housing
A pharmaceutic factory workshop producing ointments can use the following equipment at the packing stage:
- Screw and piston dosing machines
- Rezepin automatic machine
- Rotary machines
- Eccentric machines
- Disc machines
What preparation is the specific antidote in case of intoxication with iron preparations?
- Protamine sulfate
A pharmacist has a labour dispute with the pharmacy administration about rescheduling his annual vacation leave. The employee can appeal against the decision of the pharmacy administration to the following body:
- Labour disputes commission (LDC)
- Trade union committee
- Highest management bodies of pharmaceutical service at the regional level
- MoH of Ukraine
- Commercial court
A pharmacist has prepared solution of ethacrydine lactate. Name the peculiarity of this substance dissolution.
- Dissolving in hot water
- Dissolving in freshly distilled water
- Dissolving in cold water
- Grinding in a mortar with water
- Dissolving in potassium iodide solution
A pharmacy received a prescription for an extemporaneous compounded drug. Specify the document that is used to set the price for such drug:
- Retail price list for drugs
- Inventory report
- Certificate of quality
- Cash receipt voucher
- Certificate of analysis
Medications Passit and Novopassit are used as tranquilizing, sedative and mild soporific agents. These medications are produced from the following grass:
- Purple passionflower
- Three-lobe beggarticks
- Garden sage
- Lesser periwinkle
Thymol is the main component of Thymus serpyllum essential oil. What is the time of harvesting for this raw herbal material?
- Peak florescence period
- In autumn after above-ground part of a plant dies-off
- During peak of sap movement
- During fruiting
- Beginning of vegetation
An essential oil is a component of such compound drugs as: Inhalypt, Corvalol, Pinosol, Corvaldin, tooth drops. What raw herbal material is a source of this essential oil?
- Folia Menthae piperitae
- Folia Betulae
- Folia Urticae
- Folia Agavae
- Folia Absinthii
When developing the system of marketing communications, a company should consider the characteristics of each market promotion means applied for a drug. Which of the following characteristics is typical for advertising?
- Depersonalization (non-personal communication)
- Non-mass communication
- Two-way communication
- All answers are correct
- There is no correct answer
A pharmaceutical factory produces suspensions and emulsions. Specify the equipment that is used for dispersion and mixing in liquid medium:
- Rotor-pulsation apparatus, colloid mixers
- Drum mixers
- Oscillating mixers
- Anchor mixers
- Gate mixers
What reagent is used to detect calcium admixture in medicinal substances?
- Ammonium oxalate
- Barium chloride
- Potassium carbonate
- Silver nitrate
- Sodium sulfate
A pharmacy received a prescription for vaseline-lanoline based eye ointment. What proportion of vaseline to lanoline should be chosen by a pharmacist to make the ointment base?
A pharmacist has made an althaea root tincture. What proportion of raw herbal material to extractant was chosen by the pharmacist to make this tincture?
Collective labour agreement is concluded by a trade union committee with an enterprise owner on behalf of the workforce. Any collective agreement is worked out in written form. Which article of the Labor Code regulates the duration of the collective agreement?
To stimulate sales a pharmaceutical wholesale company grants its customers a discount according to the social contract and on condition of their loyalty. Specify the type of discount:
- Discounts for quantity of purchased goods
One of the quality indicators for finished ampoules is lack of residual stress in the glass. Which operation at the "Preparation of ampoules to be filled"stage eliminates this imperfection?
- Ampoule annealing
- Capillary opening
- Ampoule washing
- Ampoule drying
- Ampoule sterilization
Companies producing injectable dosage forms apply different methods of ampoule sealing. Sealing against a jet of inert gases (nitrogen, argon, carbon dioxide) is suitable for the following injection solutions:
- Easily oxidable
- Hydrolytically unstable
A pharmacist prepares a solution for injections that must be stabilized with 0,1M of hydrochloric acid solution. What solution is to be prepared?
- Calcium chloride
- Potassium chloride
- Sodium benzoate
Paracetamol substance has been sent for analysis. Reaction with the solution of iron (III) chloride resulted in blue-purple colouring. This indicates the presence of:
- Phenolic hydroxyl
- Aldehyde group
- Keto group
- Ester group
- Alcoholic hydroxyl
Production of tablets requires stage-to-stage quality control. What devices are used to determine the particle size distribution (fraction) of granules?
- Standard set of sieves
- Various vibrosieves
- Laboratory identifiers
According to the State Pharmacopoeia of Ukraine, in order to test a substance for the highest level of magnesium impurities an analytical chemist must use the following solution:
Preparations of sorrel roots can have both laxative and astringent effect. Such an effect results from the presence of the following biologically active substances:
- Anthracene derivatives and tannins
- Flavonoids and essential oils
- Essential and fatty oils
- Coumarins and phenol glycosides
- Iridoids and vitamins