A pharmaceutist has to prepare an aqueous extract of medicinal plants. What can be used as a substitute of plant material in the drug preparation?
- Standardized extract concentrate
- Liquid extract
- Thick extract
- Aromatic water
A 65-year-old female patient with a fracture of mandible has been prescribed a drug from the group of narcotic analgesics. Specify this drug:
A hypertensive patient has been prescribed a drug from the group of nonselective beta-blockers. Specify this drug:
- Neostigmine methylsulfate
- Adrenaline hydrochloride
A patient has a history of cholelithiasis. What drug should be administered to prevent biliary colic?
- Magnesium sulfate
From the pharmaceutical stock select a reversible anticholinesterase drug to be administered to the patients with atony of the intestine and urinary bladder in the postoperative period:
- Atropine sulfate
A patient after acute myocardial infarction has been recommended to take acetylsalicylic acid for 3-4 months. What effect of acetylsalicylic acid would be most relevant for this patient?
Rose essential oil is used as an antiinflammatory and antispasmodic agent. It is localized in the following excretory structures:
- Glandular spots
- Essential oil glandules
- Essential oil conceptacles
- Secretory cells
- Glandular hairs
Production, labour and socioeconomic relations between the head of a pharmaceutical company and the workforce are regulated by:
- Collective agreement
- Labour contract
- Corporate code
A pharmacy makes bulk purchases of health and hygiene products. The agent works under a contract with the manufacturer and operates on his account. The agent may be given the exclusive right to sell goods in certain regions. Specify this agent:
- Wholesale agent
- Commission agent
A pharmaceutical company has made a decision to expand its activities. The process of the company’s activity expansion by penetration into new fields of the branch is called:
A pharmacy prepares ointments with extracts. What is the way to incorporate the dry and thick extracts into the ointments?
- To triturate them first with alcohol-water-glycerol [1:6:3] mixture
- To incorporate them directly into the molten ointment base
- To dissolve them in water first
- To disperse them with a liquid which is compatible with the base
- To disperse them with ethanol
A pharmacy received a prescription: Rp.: Dibazoli0,05 Papaverini hydrochloridi 0,15 Sacchari 2,5 M. fiat pulv. Divide in partes aequales №10. Specify the weight of a single powder dose:
A pharmaceutist working at an analytical laboratory is engaged into sulfite-ion identification of a drug in compliance with the requirements of SPhU. What reagent becomes colourless in this study?
- Iodine solution
- Iron (III) chloride solution
- Ammonia solution
- Potassium iodide solution
- Potassium nitrate solution
Select a drug for the treatment of bronchial asthma from the group of fi2-agonists:
Ampules are produced of glass with appropriate heat resistance. An ampule would meet the requirements of technical standards if the ampule glass has the following characteristic:
- Thermal shock resistance
- Easy cutting of capillaries
- Quality ampule sealing
- Withstanding the stresses during production and transportation
- Protection of light-sensitive materials
Ampule quality control involves testing for chemical resistance. What methods are used to test this indicator?
- Various acid-base indicators, pH meter, gravimetric methods
- Visual, gravimetric methods
- Photoelastic method
- Autoclaving followed by titration with a solution of hydrochloric acid
- Exposing the glass samples to the action of sodium carbonate and sodium hydrocarbonate solutions
A pharmaceutist prepared the massage cream of the following composition: Beeswax 12,0 Almond oil 68,5 Spermaceti 12,0 Anhydrous lanolin 7,5 Essential oil of lavender 3 drops. Specify the cream type:
What is the function of anhydrous lanolin in the suppository mass used for suppositories prepared by hand rolling?
Plantain leaves are used for production of Plantaglucidum which has antiulcerogenic action. The plant material analysis involves quantitative determination of the following class of compounds:
What herbal drug produced form alkaloid-containing raw materials can be recommended for neurasthenia, insomnia, menopausal disorders?
- Glaucine hydrochloride
- Securinine nitrate
A pharmaceutist has prepared a suspension with a hydrophobic substance. What stabilizer is required for its preparation?
- 5% solution of methyl cellulose
- Sodium thiosulfate
- Sodium chloride
- Polyethylene oxide
A patient has been found to have pesticide intoxication. Biochemical (cholinesterase) test was positive. What pesticide is likely to have caused the intoxication?
- Ethyl mercury chloride
Which of the following sublingual drugs quickly relieves an attack of stenocardia?
Diazepam is used for the treatment of neuroses due to the following pharmacological effect:
A patient has been administered a spasmolytic from the group of muscarinic receptor antagonists as a part of the complex treatment for renal colic. Specify this drug:
One of the recent industrial medical forms that is used in pediatric practice and intended for young children unable of swallowing tablets is:
- Gelatin microcapsules
What final document is used for the preparation of the report on the discrepancies revealed in course of the inventory at the pharmacy?
- Act on the inventory results
- Inventory item description
- Commercial report
Pharmaceutical market of Ukraine comprises pharmacies of various forms of ownership. Specify the form of ownership for a community pharmacy:
- Territorial community
- Workforce of an enterprise
- Private person
- Group of shareholders
A patient with a history of allergic rhinitis has been prescribed ephedrine in form of nasal drops. The patient has significantly benefited from nasal instillation, and this stimulated him to use the drug every two hours. But under these conditions the drug appeared to be ineffective. What is the most likely cause of this phenomenon?
- Drug dependence
A pharmaceutic plant producing aerosol forms uses liquefied gases as propellents. Which of the following substances relates to the group of liquefied gases?
- Nitrous oxide
- Methylene chloride
- Ethylene chloride
A pharmaceutist has to prepare a drug by the prescription: Rp.: Natrii hydrocarbonatis 2,0 Natrii benzoatis 1,5 Liquoris Ammonii anisatis 4 ml Aquae Mentae 100 ml M.D.S. 1 tablespoon 3 times a day. Specify the component that is added in the first place:
- Mint water
- Sugar syrup
- Liquoris Ammonii anisatis
- Sodium hydrogen carbonate
- Sodium benzoate
A person got poisoned with an unknown substance. Chemico-toxicological test for the isolated toxin with Dragendorff’s, Sonnenschein’s, Schei-bler’s reagents caused setting of sediments. The specific study should be focused on the following group of toxic substances:
- Alkaloids and nitrogen-containing compounds
- Metal toxins
- Hydrocyanic acid
- Methyl alcohol
- Ammonia and its salts
A laboratory for drug quality control checks the quality of the drug substance nitrofural (furacilin). The chemical denomination of this drug is:
- 5-Nitro-2-furaldehyde semicarbazone
- 1-(5-Nitrofurfurilidenamino)imidazolidine-2 ,4-dione
A 25-year-old patient with frequent migraine attacks has been prescribed sumatriptan. Specify the mechanism of its action:
- Selective agonist of 5 — HTi-serotonin receptors
- Selective antagonist of 5 — HTX-serotonin receptors
- Nonselective «-blocker
- Stimulator of в-adrenergic receptors
- Selective «-blocker
A 43-year-old patient with a severe form of rheumatoid arthritis has been administered a certain drug for background therapy. Specify this drug:
- Diclofenac sodium
In order to analyze marketing opportunities and make a forecast of the market position a pharmaceutical company can use a matrix allowing the company to find new markets (geographical) or identify new areas of using traditional medicines. What matrix is used by a pharmaceutical company to identify its market position?
- Ansoff matrix
- Boston Consulting Group matrix
- Porter’s matrix
- Matrix of competitive advantages
- Competitive force models
A female 49-year-old patient complains of compressing headache in the occipital region, dizziness, increased AP. The patient has a history of diabetes melli-tus type II. What diuretic DOES NOT affect the blood glucose level?
- Ethacrynic acid
A 65-year-old patient complains of nausea, vomiting, lethargy, seeing yellow spots in front of his eyes. The patient daily takes 0,25 mg of digoxin, 100 mg of aspecardum, 50 mg of metoprolol. What pathological condition is this syndrome typical for?
- Glycoside intoxication
- Food poisoning
- Withdrawal syndrome
- Hypersensitivity reaction
Pharmaceutical plants produce ointments on various bases. Specify the ointment base having the most pronounced osmotic properties:
- Polyethylene oxide
- Vaseline, lanolin
- Methyl cellulose
- Hydrogenated fat
Ampule workshop of a pharmaceutical factory produces the procaine hydrochloride solution. This solution is stabilized by adding:
- 0,1 mol/l of hydrochloric acid solution
- 0,1 mol/l of sodium hydroxide solution
- 0,1 mol/l of sodium hydrogen carbonate solution
- 20,0 of sodium hydrogen carbonate
- 1,5 g of amino-propylene glycol
Some alkaline solution was added to the alcohol solution of ftivazide, causing the solution to change colour from the light yellow to the orange-yellow. Subsequent addition of hydrochloric acid made the solution become again light yellow, and then orange-yellow. What properties of ftivazide are proved by this reaction?
When atropine sulfate is tested for purity, the alkaloids and degradation products are detected by TLC. For this purpose the chromatographic plate is sprayed with a solution of:
- Potassium iodobismuthate
- Acetic-hydrochloric dini- trophenylhydrazine
- Tetrabutylammonium hydroxide
Specific impurity of thiosulfates in Natrii iodidum and Kalii iodidum is identified by adding starch and iodine solutions. The absence of impurities is proved by:
- Blue colour
- Yellow colour
- Disappearance of the blue colour
- White precipitate
- Discolouration of the solution
Bronchodilatory effect of shortacting ^2-adrenoceptor agonist salbutamol develops after:
- 5-10 minutes
- 20-30 minutes
- 45-60 minutes
- 2-3 hours
- 4-6 hours
A12 weeks pregnant patient has been hospitalized with symptoms of acute cystitis. What antibiotic can be recommend in this case?
Issuing prescriptions and orders for drugs and medical products is regulated by the Order № 360 dated 19.07.2005 (as amended). Specify the prescription form for phenobarbital as a part of a combined dosage form:
- No prescription
- F-3 in duplicate
- Prescription forms F-1 and F-3 in duplicate
Vacation leaves for employees of pharmacies include paid annual, additional, sabbatical, social leaves, as well as unpaid leaves. What is the total duration of the paid basic and additional vacation leave?
- 59 calendar days
- 60 calendar days
- 90 calendar days
- 70 calendar days
- 65 calendar days
Representatives of the family Solanaceae are widely used in medical practice as alkaloid-containing plants. Which representative is the source for production of semi-synthetic steroid hormones?
- Solanum laciniatum
- Atropa belladonna
- Datura Stramonium
- Hyoscyamus niger
- Solanum tuberosum
After harvesting the calamus rhizomes the received material should be dried. What temperature range is required for obtaining good-quality raw material?
A pharmaceutist has to prepare 10% alcohol solution of iodine. What is the required concentration of ethanol for this purpose?