Analysis of an extract by chromatographic method revealed presence of phenyl prapanolamine. It is the metabolite of the following alkaloid:
During local anaesthetization novocai-ne solution is usually compounded with solution of adrenaline hydrochloride. What is the purpose of this action?
- Increase in smooth muscle tone
- Decrease in smooth muscle tone
- Algesthesia reduction
A 32-year-old patient takes antituberculous drugs. Some time later he has noticed that his urine turned orange. What preparation is the most likely cause of this phenomenon?
- Streptomycin sulfate
6 months after treatment a patient with coronary heart disease developed tolerance to the nitrates with prolonged action. What drug with nitrate-similar effect should be recommended in this case?
A 52-year-old patient was diagnosed with systemic amebiasis accompanied by bowels, liver and lungs affection. What preparation should be administered?
A 33-year-old woman who has been treated for chronic polyarthritis for a long time complains about arterial pressure rise, change of adipose tissue distribution, menstrual cycle disorder. What preparati- on has she taken?
- Diclofenac sodium
A pharmaceutist made a tincture of althaea root. What is the proportion of herbal crude drug and extractant?
A pharmaceutical enterprise widely applies technical and technological media of information use in order to increase efficiency of managing productive and administrative activity of an organization, to enhance labour productivity, to improve methods of planning and regulating management processes. All this is realized by means of:
- Automated management system
- Automation equipped working place
- Automated instruction and control system
- Information-management system
- Automated data retrieval system
Marketing research of certain pharmaceutical groups involves collection and analysis of primary information. This is the following type of marketing research:
- Field research
- Armchair research
- Research of drug market
- Research of drug consumers
- Research of marketing network of pharmaceutical market
An analytical laboratory carries out quantitative analysis of sodium citrate by method of ion-exchanging chromatography on a cationite. What titrated solution is to be used for the following titration of generated citric acid?
- Sodium hydroxide
- Potassium iodate
- Hydrochloric acid
- Trilon B
A pharmaceutist prepared an oil emulsion containing zinc oxide. Specify the rational method of substance incorporation:
- Suspension-type icorporation into the prepared emulsion
- Dissolution in oil
- Grinding with water for dilution of the primary emulsion
- Dissolution in water for preparation of the primary emulsion
- Dissolution in the finished emulsion
A pharmaceutist made a tincture of Adonis herb. A peculiarity of its preparation is that the active substances are derived in:
- In the neutral medium
- In the alkalescent medium
- In the alkaline medium
- In the subacid medium
- In the acid medium
Preparations made of ginseng roots have tonic and adaptogenic properties, improve mental and physical performance. If the ginseng tincture cannot be found in a pharmacy, it can be substituted by the analogous preparations made of the following raw material:
- Radices Eleutherococci
- Radices Valerianae
- Radices Inulae
- Radices Ononidis
- Radices Rhei
Balance is a part of financial accounting of pharmacies. What index is reflected in the assets of the balance sheet?
- Residual value of fixed assets
- Retail turnover
- Wholesale turnover
- Proceeds of a pharmacy
- Salary costs
The market is characterized by the following conditions: a big number of salespersons and customers who don’t make any influence upon the level of current prices; availability of uniform and interchangeable competing products; lack of price restrictions. What type of market is it?
- Market of pure competition
- Market of monopolistic competition
- Oligopolistic market
- Market of pure monopoly
If the internal surface of buckthorn rind is moistened with 5% alkaline solution, it becomes cherry-red colouring. This is the evidence of presence of the following substance:
- Anthracene derivatives
A pharmacy technologist received an ointment formulation: Rp.: Unguentum Resorcini 1,5% -10,0 Da. Signa. To be applied on the affected skin areas. The pharmaceutist incorporated dry medical substance into the ointment by the following way:
- Trituration with a few drops of vaseline oil
- Trituration with a few drops of ethyl alcohol
- Trituration with a few drops of water
- Adding to the fused vaseline
- Trituration with a part of vaseline
A pharmacy analyst can verify presence of iron cation (II) in a drug formulation by means of the following solution:
- Ammonium sulfide
- Sodium chloride
- Magnesium sulfate
- Potassium bromide
- Sodium phosphate
An advance holder (accountant) received money from the cash fund of an enterprise for purchase of office accessories. After the cash advance the advance holder must submit the statement of application of funds no later than:
- On the next working day
- In three working days
- In ten working days
- In a week
- There is no deadline
Choose an antiseptic from the group of halogen containing drugs that can be included into the first-aid kit for a child going to a summer camp:
- Alcoholic iodine solution
- Brilliant green solution
- Copper sulfate solution
- Methylene blue solution
- Formaldehyde solution
A pharmacy received a new-generation nonsteroid anti-inflammatory drug "meloxicam"that mainly blocks cyclooxygenase-2. What advantages does this preparation have in comparison with other nonsteroid anti-inflammatory drugs?
- Minimal side effect on alimentary tract
- Evident myospasmolytic action
- Interferonogenic properties
- Minimal side effect on hematogenesis
- Significant inhibition of protease activity
Leaves of belladonna, henbane and datura containing tropane alkaloids must be stored according to the following list requirements:
- B list (these drug substances require caution in handling, storage or use)
- A list (poisonous drug substances)
- General sales list
- Essential oil materials list
- List of substances equivalent to narcotics
A patient suffering from essential hypertension has increased concentration of renin in blood plasma. Which pharmacological group should be preferred for this patient treatment?
- ACE inhibitors
- Blockers of calcium channels
A patient suffering from stomach ulcer was prescribed almagel. Which of its pharmacological properties is intended for treatment of this pathology?
- HCl neutralization
- Local anaesthetization
- Blocking the H2-histamine receptors
- Blocking the muscarinic choli-noreceptors
- Anti-inflammatory action
One of the ways to derive essential oil is enfleurage, or maceration. Essential oil can be derived by enfleurage from the following herbal raw material:
- Petals of Damascus rose
- Lemon skin
- Coriander fruits
- Mint leaves
- Camomile flowers
A pharmaceutist and a pharmacy manager were involved into the labour dispute about carry over of vacation time. The pharmaceutist applied to the council of conciliation. The council should consider his application within the following period:
- 10 days
- 5 days
- 3 days
- 1 week
- 1 month
All the medications require special storage conditions according to their physical and physicochemical properties. Ampouled solution of sodium adenosine triphosphate (ATP) should be stored under the following temperature:
- 3 - 5°C
- 0 - 2°C
- 7 - 10oC
- 12 - 15oC
Quality control of tablets produced at a pharmaceutical enterprise involves quantitative determination of such subsidiary substances as talc and aerosil. What method is applied for such determination?
A 52-year-old patient had myocardial infarction and was discharged from the hospital after the stationery treatment. What daily dose of acetylsalicylic acid should be administered in order to prevent thrombosis?
- 100 mg
- 500 mg
- 1000 mg
- 200 mg
- 50 mg
An analyst of a pharmaceutical storehouse received the substance of hydrogen peroxide for analysis. Quantitative determination of this drug should be performed by permanganatometric method. According to the analytical normative document, titration should be carried out till the solution turns:
- Dark blue
A patient suffering from ulcer disease was prescribed famotidine. What is the mechanism of its action?
- Block of H2-histamine receptors
- Block of H і-histamine receptors
- Block of muscarinic cholinoreceptors
- Inhibition of adenosine triphosphatase activity
- Block of cholinoreceptors of sympathetic ganglions
Ophthalmic drops are produced on the base of concentrated riboflavin solution (1:5000). How much solution should be taken if the formulation says "0,001 of riboflavin"?
While producing phytopreparations and organotherapeutic preparations different kinds of dryers are used. What dryer would be the most effective for drying thermolabile compounds?
- Roller dryer
- Band dryer
- Drying oven
- Drum dryer
Choose an optimal antibacterial drug for the mycoplasmal pneumonia treatment:
An analytical laboratory received substance of citric acid for the analysis. According to the requirements of the Ukrainian State Pharmacopoeia, citric acid can be determined by method of:
According to the requirements of the Ukrainian State Pharmacopoeia, the amount of calcium gluconate can be determined by the chelatometric method. What solution should be used as a titrant?
- Sodium edetate
- Potassium permanganate
- Iodine monochloride
- Argentum nitrate
- Hydrochloric acid
Tannins have astringent effect and are used for treatment of colitis, enterocolitis, diarrhea. What herbal raw material contains a lot of tannins?
- Fructus Myrtilli
- Fructus Sambucci nigri
- Fructus Ribes nigri
- Fructus Rhamni catharticae
- Fructus Frangulae
Anthracene derivatives of emodi-ne group exhibit purgative effect. What herbal raw material contains large quantity of anthracene derivatives of emodine group?
- Buckthorn fruits
- Elder fruits
- Currants fruits
- Bilberry fruits
- Alder buckthorn fruits
Codeine can be derived for medical purposes out of a plant alkaloid by means of semisynthetic method. Name this alkaloid:
Theory of management currently marks out four the most important approaches to the management. Choose the approach that is NOT USED in the theory of management:
- Approach from the position of different schools identification
Therapeutic department of a municipal hospital purchases medical products in a pharmacy. The wares will be dispensed from the stores department on presentation of the following document:
- Delivery order
- Cash book
- Prescription register
- Inventory report
- Register of laboratory packing works
In order to determine the purity a drop of lavender essential oil was applied on a strip of filter paper and warmed up in the stream of warm air. Some time later the stain increased in diameter. What impurity substance was found in the lavender oil?
- Fatty or mineral oil
- Diethyl ether
A doctor prescribed a patient 100 ml of tincture made out of 0,25 of Herba Thermopsidis. How much dried concentrated extract of Herba Thermopsidis should be weighed by a pharmaceutist?
- 0,25 g
- 0,5 g
- 0,3 g
- 0,2 g
- 0,1 g
A patient has ordered 50 g of zinc ointment. How much zinc and Vaseline should be weighed by a pharmaceutist?
- 5,0 g and 45,0 g
- 10,0 g and 40,0 g
- 2,5 g and 47,5 g
- 1,0 g and 49,0 g
- 0,5 g and 49,5 g
A patient got an injection of 0,25% novocaine solution for the purpose of anaesthetization. Suddenly the patient has presented with red spots, intense sweating, tachycardia, bronchospasm, edema of nasal mucous membrane. What is the cause of this complication?
- Immediate allergy
- Delayed allergy
- Local irritation
- Abstinence syndrome
In Ukraine the out-patients are supplied with narcotic and psychotropic drugs only by prescription. Medicoprophylactic institutions receive prescription blanks (Form 3) from the following source:
- Pharmacy storehouse
- City’s health department
- Wholesale companies
- Pharmaceutical corporation
Injection solutions of salts derived from weak acids and strong bases require stabilization. What stabilizers are used for these solutions?
- 0,1 М solution of sodium hydroxide
- 0,1 М solution of perchloric acid
- Trilon B
- Ascorbic acid
100 ml of 0,9% sodium chloride solution were prepared according to the doctor’s prescription. What sterilization schedule is required for this solution?
- 120oC - 8 minutes
- 120oC -12 minutes
- 120oC -15 minutes
- 180oC - 30 minutes
- 100oC -15 minutes
During digitoxin therapy for chronic cardiac insufficiency, a patient developed signs of intoxication with this preparation. The patient was prescribed unithiol. What is the mechanism of unithiol action in case of intoxication with cardiac glycosides?
- Reduction of K+-Na+-adenosine triphosphatase
- Binding of calcium ions
- Increase of sodium concentration in the cardiomyocytes
- Increased potassium permeability in the cardiomyocytes
- Binding of glycoside into the complex compound
A pharmacy got a formulation of a mixture containing manzanita decoction and belladonna extract. What is the reason for incompatibility between these components?
- Oxidation-reduction processes
- Emission of gaseous substances
- Coagulation of colloid systems